Released protease-nexin regulates cellular binding, internalization, and degradation of serine proteases.

Protease-nexin (PN), a component released by normal human fibroblasts into culture medium, forms covalent linkages with thrombin (Th) and the urinary plasminogen activator urokinase, apparently with their catalytic site serines. The present studies explored the function of PN by examining the intera...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Low, D A, Baker, J B, Koonce, W C, Cunningham, D D
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1981
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319341/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7017731/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.4.2340
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