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Released protease-nexin regulates cellular binding, internalization, and degradation of serine proteases.

Protease-nexin (PN), a component released by normal human fibroblasts into culture medium, forms covalent linkages with thrombin (Th) and the urinary plasminogen activator urokinase, apparently with their catalytic site serines. The present studies explored the function of PN by examining the intera...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Low, D A, Baker, J B, Koonce, W C, Cunningham, D D
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1981
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319341/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7017731/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.4.2340
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