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p53 responsive elements in human retrotransposons

Long interspersed nuclear elements-1 (L1s) are highly repetitive DNA elements that are capable of altering the human genome through retrotransposition. To protect against L1 retroposition, the cell downregulates the expression of L1 proteins by various mechanisms, including high-density cytosine met...

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Detalhes bibliográficos
Main Authors: Harris, CR, DeWan, A, Zupnick, A, Normart, R, Gabriel, A, Prives, C, Levine, AJ, Hoh, J
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193277/
https://ncbi.nlm.nih.gov/pubmed/19718052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.246
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