Partial immune reconstitution of X-linked hyper IgM syndrome with recombinant CD40 ligand

X-linked hyper IgM syndrome (XHM) is a combined immune deficiency disorder caused by genetic alterations in CD40 ligand. The purpose of this study was to investigate the safety and efficacy of recombinant CD40 ligand (rCD40L) in the treatment of the disease. Three children were administered rCD40L s...

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Main Authors: Jain, Ashish, Kovacs, Joseph A., Nelson, David L., Migueles, Stephen A., Pittaluga, Stefania, Fanslow, William, Fan, Xiying, Wong, Duane W., Massey, Justin, Hornung, Ronald, Brown, Margaret R., Spinner, Jacob J., Liu, Shuying, Davey, Victoria, Hill, Harry A., Ochs, Hans, Fleisher, Thomas A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2011
Assuntos:
Clinical Trials and Observations
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193261/
https://ncbi.nlm.nih.gov/pubmed/21841160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-04-351254
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