Competitive Selection from Single Domain Antibody Libraries Allows Isolation of High-Affinity Antihapten Antibodies That Are Not Favored in the llama Immune Response

Single-domain antibodies (sdAbs) found in camelids, lack a light chain and their antigen-binding site sits completely in the heavy-chain variable domain (VHH). Their simplicity, thermostability, and ease in expression have made VHHs highly attractive. While this has been successfully exploited for m...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Rosa, Sofia Tabares-da, Rossotti, Martin, Carleiza, Carmen, Carrión, Federico, Pritsch, Otto, Ahn, Ki Chang, Last, Jerold A., Hammock, Bruce D, González-Sapienza, Gualberto
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193053/
https://ncbi.nlm.nih.gov/pubmed/21827167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac201824z
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk