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The Two-Pathway Model of the Biological Catch-Bond as a Limit of the Allosteric Model

Catch-binding is a counterintuitive phenomenon in which the lifetime of a receptor/ligand bond increases when a force is applied to break the bond. Several mechanisms have been proposed to rationalize catch-binding. In the two-pathway model, the force drives the system away from its native dissociat...

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Detalhes bibliográficos
Main Authors: Pereverzev, Yuriy V., Prezhdo, Eugenia, Sokurenko, Evgeni V.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192973/
https://ncbi.nlm.nih.gov/pubmed/22004757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.09.005
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