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The Two-Pathway Model of the Biological Catch-Bond as a Limit of the Allosteric Model
Catch-binding is a counterintuitive phenomenon in which the lifetime of a receptor/ligand bond increases when a force is applied to break the bond. Several mechanisms have been proposed to rationalize catch-binding. In the two-pathway model, the force drives the system away from its native dissociat...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Biophysical Society
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3192973/ https://ncbi.nlm.nih.gov/pubmed/22004757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.09.005 |
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