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Selection for animal cells that express the Escherichia coli gene coding for xanthine-guanine phosphoribosyltransferase.

Cultured monkey (TC7) and mouse (3T6) cells synthesize an Excherichia coli enzyme, xanthine-guanine phosphoribosyltransferase (XGPRT; 5-phospho-alpha-D-ribose-1-diphosphate:xanthine phosphoribosyltransferase, EC 2.4.2.22), after transfection with DNA vectors carrying the corresponding bacterial gene...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Mulligan, R C, Berg, P
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1981
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319285/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7017722/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.4.2072
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