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The Dynamics of Supply and Demand in mRNA Translation

We study the elongation stage of mRNA translation in eukaryotes and find that, in contrast to the assumptions of previous models, both the supply and the demand for tRNA resources are important for determining elongation rates. We find that increasing the initiation rate of translation can lead to t...

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Autors principals: Brackley, Chris A., Romano, M. Carmen, Thiel, Marco
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192816/
https://ncbi.nlm.nih.gov/pubmed/22022250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002203
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