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Nuclear history of a pre-mRNA determines the translational activity of cytoplasmic mRNA.
The pathways of synthesis and maturation of pre-messenger RNA in the nucleus have a direct effect on the translational efficiency of mRNA in the cytoplasm. The transcription of intron-less mRNA in vivo directs this mRNA towards translational silencing. The presence of an intron at the 5' end of...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
1998
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170555/ https://ncbi.nlm.nih.gov/pubmed/9524132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.7.2107 |
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