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In vitro susceptibility to pyrimethamine of DHFR I164L single mutant Plasmodium falciparum
BACKGROUND: Recently, Plasmodium falciparum parasites bearing Pfdhfr I164L single mutation were found in Madagascar. These new mutants may challenge the use of antifolates for the intermittent preventive treatment of malaria during pregnancy (IPTp). Assays with transgenic bacteria suggested that I16...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3192713/ https://ncbi.nlm.nih.gov/pubmed/21951962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-10-283 |
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