In vitro susceptibility to pyrimethamine of DHFR I164L single mutant Plasmodium falciparum

BACKGROUND: Recently, Plasmodium falciparum parasites bearing Pfdhfr I164L single mutation were found in Madagascar. These new mutants may challenge the use of antifolates for the intermittent preventive treatment of malaria during pregnancy (IPTp). Assays with transgenic bacteria suggested that I16...

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Autores principales: Andriantsoanirina, Valérie, Durand, Rémy, Pradines, Bruno, Baret, Eric, Bouchier, Christiane, Ratsimbasoa, Arsène, Ménard, Didier
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192713/
https://ncbi.nlm.nih.gov/pubmed/21951962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-10-283
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