Urinary Excretion of 3-Hydroxyisovaleric Acid and 3-Hydroxyisovaleryl Carnitine Increases in Response to a Leucine Challenge in Marginally Biotin-Deficient Humans(2)

Experimentally increasing metabolic flux in a pathway in which an essential step is catalyzed by a vitamin-dependent enzyme (a challenge test) has been used in assessing functional vitamin status and elucidating common and alternate metabolic pathways. Conversion of 3-methylcrotonyl CoA to 3-methylg...

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Detalhes bibliográficos
Main Authors: Mock, Donald M., Stratton, Shawna L., Horvath, Thomas D., Bogusiewicz, Anna, Matthews, Nell I., Henrich, Cindy L., Dawson, Amanda M., Spencer, Horace J., Owen, Suzanne N., Boysen, Gunnar, Moran, Jeffery H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Nutrition 2011
Assuntos:
Biochemical, Molecular, and Genetic Mechanisms
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192457/
https://ncbi.nlm.nih.gov/pubmed/21918059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/jn.111.146126
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