Depurination causes mutations in SOS-induced cells.
Introduction of apurinic sites into phi X174 am3 DNA leads to loss of biological activity when measured in a transfection assay. For single-stranded DNA, approximately one apurinic site constitutes a lethal hit; for double-stranded (RFI) DNA, approximately 3.5 hits per strand are lethal. When the re...
Bewaard in:
| Gepubliceerd in: | Proc Natl Acad Sci U S A |
|---|---|
| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
1981
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319216/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6453349/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.3.1773 |
| Tags: |
Geen labels, Wees de eerste die dit record labelt!
|