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Calcineurin mediates bladder wall remodeling secondary to partial outlet obstruction

We hypothesized that the calcineurin-nuclear factor of activated T-cells (NFAT) pathway is activated following partial bladder outlet obstruction (pBOO), which would allow for pharmacologic treatment to prevent the ensuing bladder wall hypertrophy. Using a model of pBOO in male mice, we were able to...

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Autori principali: Chang, Andy Y., Sliwoski, Joanna, Butler, Stephan, Hearn, George, Lassmann, Jenny, Chacko, Samuel, Canning, Douglas A., Zderic, Stephen A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191798/
https://ncbi.nlm.nih.gov/pubmed/21775483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00586.2010
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