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Lysophosphatidic acid receptor 1 modulates lipopolysaccharide-induced inflammation in alveolar epithelial cells and murine lungs

Lysophosphatidic acid (LPA), a bioactive phospholipid, plays an important role in lung inflammation by inducing the release of chemokines and lipid mediators. Our previous studies have shown that LPA induces the secretion of interleukin-8 and prostaglandin E(2) in lung epithelial cells. Here, we dem...

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Bibliografiske detaljer
Main Authors: Zhao, Jing, He, Donghong, Su, Yanlin, Berdyshev, Evgeny, Chun, Jerold, Natarajan, Viswanathan, Zhao, Yutong
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191756/
https://ncbi.nlm.nih.gov/pubmed/21821728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00058.2011
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