Lysophosphatidic Acid Enhances Pulmonary Epithelial Barrier Integrity and Protects Endotoxin-induced Epithelial Barrier Disruption and Lung Injury

Lysophosphatidic acid (LPA), a bioactive phospholipid, induces a wide range of cellular effects, including gene expression, cytoskeletal rearrangement, and cell survival. We have previously shown that LPA stimulates secretion of pro- and anti-inflammatory cytokines in bronchial epithelial cells. Thi...

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Detalhes bibliográficos
Main Authors: He, Donghong, Su, Yanlin, Usatyuk, Peter V., Spannhake, Ernst Wm., Kogut, Paul, Solway, Julian, Natarajan, Viswanathan, Zhao, Yutong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782006/
https://ncbi.nlm.nih.gov/pubmed/19586906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.007393
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