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Tissue-specific exposure of chromatin structure at the 5' terminus of the rat preproinsulin II gene.

The 5' terminus of the rat preproinsulin II gene exhibits a tissue-dependent DNase I sensitivity. Only in the chromatin froma pancreatic beta-cell tumor, but not in liver, spleen, kidney, or brain chromatin, is a region at and before the 5' end of the gene exposed to cleavage. The region o...

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Autors principals: Wu, C, Gilbert, W
Format: Artigo
Idioma:Inglês
Publicat: 1981
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC319174/
https://ncbi.nlm.nih.gov/pubmed/6262815
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