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Tissue-specific exposure of chromatin structure at the 5' terminus of the rat preproinsulin II gene.

The 5' terminus of the rat preproinsulin II gene exhibits a tissue-dependent DNase I sensitivity. Only in the chromatin froma pancreatic beta-cell tumor, but not in liver, spleen, kidney, or brain chromatin, is a region at and before the 5' end of the gene exposed to cleavage. The region o...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Wu, C, Gilbert, W
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1981
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319174/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6262815/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.3.1577
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