Zip14 is a complex broad-scope metal-ion transporter whose functional properties support roles in the cellular uptake of zinc and nontransferrin-bound iron

Recent studies have shown that overexpression of the transmembrane protein Zrt- and Irt-like protein 14 (Zip14) stimulates the cellular uptake of zinc and nontransferrin-bound iron (NTBI). Here, we directly tested the hypothesis that Zip14 transports free zinc, iron, and other metal ions by using th...

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Hauptverfasser: Pinilla-Tenas, Jorge J., Sparkman, Brian K., Shawki, Ali, Illing, Anthony C., Mitchell, Colin J., Zhao, Ningning, Liuzzi, Juan P., Cousins, Robert J., Knutson, Mitchell D., Mackenzie, Bryan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2011
Schlagworte:
Membrane Transporters, Ion Channels and Pumps
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191563/
https://ncbi.nlm.nih.gov/pubmed/21653899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00479.2010
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