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A novel single cDNA amplicon pyrosequencing method for high-throughput, cost-effective sequence-based HLA class-I genotyping
HLA genotype influences the immune response to pathogens and transplanted tissues; accurate HLA genotyping is critical for clinical and research applications. Sequence-based HLA typing is limited by the cost of Sanger sequencing genomic DNA and resolving cis/trans ambiguities, hindering both studies...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3191540/ https://ncbi.nlm.nih.gov/pubmed/20650293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humimm.2010.07.012 |
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