Systematic punctuation of eukaryotic DNA by A+T-rich sequences.

Isodenaturation of avian and mammalian DNA of Mr greater than 2.5 X 10(8) in 85% (vol/vol) formamide led to the observation by electron microscopy of A+T-rich zones ("AT-rich linkers") of 300-3000 base pairs which are distributed over the entire genome in a characteristic pattern. Linkers...

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Autors principals: Moreau, J, Matyash-Smirniaguina, L, Scherrer, K
Format: Artigo
Idioma:Inglês
Publicat: 1981
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC319126/
https://ncbi.nlm.nih.gov/pubmed/6940161
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