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Autophagy and lipid metabolism coordinately modulate lifespan in germline-less C. elegans

BACKGROUND: The cellular recycling process of autophagy is emerging as a key player in several longevity pathways in C. elegans; however, the underlying mechanism by which autophagy modulates aging is currently unknown. Here, we identify a role for autophagy in the extended lifespan induced by germl...

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Hlavní autoři: Lapierre, Louis R., Gelino, Sara, Meléndez, Alicia, Hansen, Malene
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191188/
https://ncbi.nlm.nih.gov/pubmed/21906946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2011.07.042
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