Human FasL Gene Is a Target of β-Catenin/T-Cell Factor Pathway and Complex FasL Haplotypes Alter Promoter Functions

FasL expression on human immune cells and cancer cells plays important roles in immune homeostasis and in cancer development. Our previous study suggests that polymorphisms in the FasL promoter can significantly affect the gene expression in human cells. In addition to the functional FasL SNP -844C&...

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Autori principali: Wu, Jianming, Richards, Maureen H., Huang, Jinhai, Al-Harthi, Lena, Xu, Xiulong, Lin, Rui, Xie, Fenglong, Gibson, Andrew W., Edberg, Jeffrey C., Kimberly, Robert P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191176/
https://ncbi.nlm.nih.gov/pubmed/22022540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026143
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