Human FasL Gene Is a Target of β-Catenin/T-Cell Factor Pathway and Complex FasL Haplotypes Alter Promoter Functions

FasL expression on human immune cells and cancer cells plays important roles in immune homeostasis and in cancer development. Our previous study suggests that polymorphisms in the FasL promoter can significantly affect the gene expression in human cells. In addition to the functional FasL SNP -844C&...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wu, Jianming, Richards, Maureen H., Huang, Jinhai, Al-Harthi, Lena, Xu, Xiulong, Lin, Rui, Xie, Fenglong, Gibson, Andrew W., Edberg, Jeffrey C., Kimberly, Robert P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2011
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191176/
https://ncbi.nlm.nih.gov/pubmed/22022540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026143
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