Bioluminescent Orthotopic Mouse Models of Human Localized Non-Small Cell Lung Cancer: Feasibility and Identification of Circulating Tumour Cells

BACKGROUND: Preclinical models of non-small cell lung cancer (NSCLC) require better clinical relevance to study disease mechanisms and innovative therapeutics. We sought to compare and refine bioluminescent orthotopic mouse models of human localized NSCLC. METHODS: Athymic nude mice underwent subcut...

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Main Authors: Mordant, Pierre, Loriot, Yohann, Lahon, Benoit, Castier, Yves, Lesèche, Guy, Soria, Jean-Charles, Vozenin, Marie-Catherine, Decraene, Charles, Deutsch, Eric
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191172/
https://ncbi.nlm.nih.gov/pubmed/22022511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026073
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