SPARC regulates collagen interaction with cardiac fibroblast cell surfaces

Cardiac tissue from mice that do not express secreted protein acidic and rich in cysteine (SPARC) have reduced amounts of insoluble collagen content at baseline and in response to pressure overload hypertrophy compared with wild-type (WT) mice. However, the cellular mechanism by which SPARC affects...

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Detalhes bibliográficos
Main Authors: Harris, Brett S., Zhang, Yuhua, Card, Lauren, Rivera, Lee B., Brekken, Rolf A., Bradshaw, Amy D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Signaling and Stress Response
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191098/
https://ncbi.nlm.nih.gov/pubmed/21666116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01247.2010
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