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SPARC and the N-propeptide of collagen I influence fibroblast proliferation and collagen assembly in the periodontal ligament

The periodontal ligament (PDL) is a fibrous connective tissue that anchors tooth cementum into alveolar bone. Secreted protein acidic and rich in cysteine (SPARC) is a collagen-binding matricellular protein known to influence collagen fiber assembly in the PDL. In contrast, functional properties of...

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Bibliographic Details
Published in:PLoS One
Main Authors: Rosset, Emilie Moore, Trombetta-eSilva, Jessica, Hepfer, Glenn, Yao, Hai, Bradshaw, Amy Dodd
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330531/
https://ncbi.nlm.nih.gov/pubmed/28245286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173209
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