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The 90-kDa Heat-shock Protein (Hsp90)-binding Immunophilin FKBP51 Is a Mitochondrial Protein That Translocates to the Nucleus to Protect Cells against Oxidative Stress

Confocal microscopy images revealed that the tetratricopeptide repeat motif (TPR) domain immunophilin FKBP51 shows colocalization with the specific mitochondrial marker MitoTracker. Signal specificity was tested with different antibodies and by FKBP51 knockdown. This unexpected subcellular localizat...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Gallo, Luciana I., Lagadari, Mariana, Piwien-Pilipuk, Graciela, Galigniana, Mario D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191054/
https://ncbi.nlm.nih.gov/pubmed/21730050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.256610
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