The hsp90-FKBP52 Complex Links the Mineralocorticoid Receptor to Motor Proteins and Persists Bound to the Receptor in Early Nuclear Events

In this study, we demonstrate that the subcellular localization of the mineralocorticoid receptor (MR) is regulated by tetratricopeptide domain (TPR) proteins. The high-molecular-weight immunophilin (IMM) FKBP52 links the MR-hsp90 complex to dynein/dynactin motors favoring the cytoplasmic transport...

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Huvudupphovsmän: Galigniana, Mario D., Erlejman, Alejandra G., Monte, Martín, Gomez-Sanchez, Celso, Piwien-Pilipuk, Graciela
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2010
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820887/
https://ncbi.nlm.nih.gov/pubmed/20038533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01190-09
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