The hsp90-FKBP52 Complex Links the Mineralocorticoid Receptor to Motor Proteins and Persists Bound to the Receptor in Early Nuclear Events

In this study, we demonstrate that the subcellular localization of the mineralocorticoid receptor (MR) is regulated by tetratricopeptide domain (TPR) proteins. The high-molecular-weight immunophilin (IMM) FKBP52 links the MR-hsp90 complex to dynein/dynactin motors favoring the cytoplasmic transport...

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Main Authors: Galigniana, Mario D., Erlejman, Alejandra G., Monte, Martín, Gomez-Sanchez, Celso, Piwien-Pilipuk, Graciela
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2010
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820887/
https://ncbi.nlm.nih.gov/pubmed/20038533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01190-09
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