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Crystal Structure of the E2 Domain of Amyloid Precursor Protein-like Protein 1 in Complex with Sucrose Octasulfate

Missense mutations in the amyloid precursor protein (APP) gene can cause familial Alzheimer disease. It is thought that APP and APP-like proteins (APLPs) may play a role in adhesion and signal transduction because their ectodomains interact with components of the extracellular matrix. Heparin bindin...

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Bibliografski detalji
Glavni autori: Xue, Yi, Lee, Sangwon, Wang, Yongcheng, Ha, Ya
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191016/
https://ncbi.nlm.nih.gov/pubmed/21715329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.219659
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