T-LAK Cell-originated Protein Kinase (TOPK) Phosphorylation of MKP1 Protein Prevents Solar Ultraviolet Light-induced Inflammation through Inhibition of the p38 Protein Signaling Pathway

Solar UV radiation is a major environmental factor that causes DNA damage, inflammation, and even skin cancer. T-LAK cell-originated protein kinase (TOPK) is expressed widely in both normal and cancer cells and functions to inhibit apoptosis and promote carcinogenesis. However, its function in infla...

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Autores principales: Li, Shengqing, Zhu, Feng, Zykova, Tatyana, Kim, Myoung Ok, Cho, Yong Yeon, Bode, Ann M., Peng, Cong, Ma, Weiya, Carper, Andria, Langfald, Alyssa, Dong, Zigang
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191001/
https://ncbi.nlm.nih.gov/pubmed/21715333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.225813
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