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Involvement of Insulin-like Growth Factor-binding Protein-3 in the Effects of Histone Deacetylase Inhibitor MS-275 in Hepatoma Cells

Insulin-like growth factor-binding protein-3 (IGFBP-3) expression is frequently suppressed in liver cancers and can be reactivated by histone deacetylase (HDAC) inhibition. This study examined the role of IGFBP-3 in mediating the effects of the HDAC inhibitor MS-275 in liver cancer cells and identif...

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Detalhes bibliográficos
Main Authors: Lin, Wen Hui, Martin, Janet L., Marsh, Deborah J., Jack, Michelle M., Baxter, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190994/
https://ncbi.nlm.nih.gov/pubmed/21737444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.263111
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