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Direct visualization of receptors for thyrotropin-releasing hormone with a fluorescein-labeled analog.
Thyrotropin-releasing hormone (TRH) binds to specific receptors on GH4C1 pituitary tumor cells. A fluorescently labeled analog of TRH was synthesized by coupling pGlu-His-ProNH(CH2)6NH2 to fluorescein isothiocyanate. The fluorescein-labeled peptide (FL-TRH) stimulated prolactin synthesis and release...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1981
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319099/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6264450/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.1.587 |
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