Direct visualization of receptors for thyrotropin-releasing hormone with a fluorescein-labeled analog.

Thyrotropin-releasing hormone (TRH) binds to specific receptors on GH4C1 pituitary tumor cells. A fluorescently labeled analog of TRH was synthesized by coupling pGlu-His-ProNH(CH2)6NH2 to fluorescein isothiocyanate. The fluorescein-labeled peptide (FL-TRH) stimulated prolactin synthesis and release...

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Bibliographic Details
Main Authors: Halpern, J, Hinkle, P M
Format: Artigo
Language:Inglês
Published: 1981
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC319099/
https://ncbi.nlm.nih.gov/pubmed/6264450
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