Altered Toll-like Receptor 2-mediated Endotoxin Tolerance Is Related to Diminished Interferon β Production

Induction of endotoxin tolerance leads to a reduced inflammatory response after repeated challenge by LPS and is important for resolution of inflammation and prevention of tissue damage. Enterobacterial LPS is recognized by the TLR4 signaling complex, whereas LPS of some non-enterobacterial organism...

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Detalhes bibliográficos
Main Authors: Zaric, Svetislav S., Coulter, Wilson A., Shelburne, Charles E., Fulton, Catherine R., Zaric, Marija S., Scott, Aaron, Lappin, Mark J., Fitzgerald, Denise C., Irwin, Christopher R., Taggart, Clifford C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190989/
https://ncbi.nlm.nih.gov/pubmed/21705332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.252791
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