Characterization of the Deoxynucleotide Triphosphate Triphosphohydrolase (dNTPase) Activity of the EF1143 Protein from Enterococcus faecalis and Crystal Structure of the Activator-Substrate Complex

The EF1143 protein from Enterococcus faecalis is a distant homolog of deoxynucleotide triphosphate triphosphohydrolases (dNTPases) from Escherichia coli and Thermus thermophilus. These dNTPases are important components in the regulation of the dNTP pool in bacteria. Biochemical assays of the EF1143...

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Bibliographische Detailangaben
Hauptverfasser: Vorontsov, Ivan I., Minasov, George, Kiryukhina, Olga, Brunzelle, Joseph S., Shuvalova, Ludmilla, Anderson, Wayne F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Enzymology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190883/
https://ncbi.nlm.nih.gov/pubmed/21757692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.250456
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