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Mechanisms of Slower Nitric Oxide Uptake by Red Blood Cells and Other Hemoglobin-containing Vesicles

Nitric oxide (NO) acts as a smooth muscle relaxation factor and plays a crucial role in maintaining vascular homeostasis. NO is scavenged rapidly by hemoglobin (Hb). However, under normal physiological conditions, the encapsulation of Hb inside red blood cells (RBCs) significantly retards NO scaveng...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Azarov, Ivan, Liu, Chen, Reynolds, Hannah, Tsekouras, Zaharo, Lee, Janet S., Gladwin, Mark T., Kim-Shapiro, Daniel B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190873/
https://ncbi.nlm.nih.gov/pubmed/21808057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.228650
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