Dynamic Changes in Binding of Immunoglobulin Heavy Chain 3′ Regulatory Region to Protein Factors during Class Switching

The 3′ regulatory region (3′ RR) of the Igh locus works at long distances on variable region (V(H)) and switch region (I) region promoters to initiate germ line (non-coding) transcription (GT) and promote class switch recombination (CSR). The 3′ RR contains multiple elements, including enhancers (hs...

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Bibliographische Detailangaben
Hauptverfasser: Chatterjee, Sanjukta, Ju, Zhongliang, Hassan, Rabih, Volpi, Sabrina A., Emelyanov, Alexander V., Birshtein, Barbara K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Gene Regulation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190736/
https://ncbi.nlm.nih.gov/pubmed/21685395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.243543
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