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Structure and Mechanism of the Diiron Benzoyl-Coenzyme A Epoxidase BoxB

The coenzyme A (CoA)-dependent aerobic benzoate metabolic pathway uses an unprecedented chemical strategy to overcome the high aromatic resonance energy by forming the non-aromatic 2,3-epoxybenzoyl-CoA. The crucial dearomatizing reaction is catalyzed by three enzymes, BoxABC, where BoxA is an NADPH-...

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Detalhes bibliográficos
Main Authors: Rather, Liv J., Weinert, Tobias, Demmer, Ulrike, Bill, Eckhard, Ismail, Wael, Fuchs, Georg, Ermler, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190730/
https://ncbi.nlm.nih.gov/pubmed/21632537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.236893
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