Φορτώνει......
The Extracellular Regulated Kinase-1 (ERK1) Controls Regulated α-Secretase-mediated Processing, Promoter Transactivation, and mRNA Levels of the Cellular Prion Protein
The α-secretases A disintegrin and metalloprotease 10 (ADAM10) and ADAM17 trigger constitutive and regulated processing of the cellular prion protein (PrP(c)) yielding N1 fragment. The latter depends on protein kinase C (PKC)-coupled M1/M3 muscarinic receptor activation and subsequent phosphorylatio...
Αποθηκεύτηκε σε:
Κύριοι συγγραφείς: | , , , , , , , , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
American Society for Biochemistry and Molecular Biology
2011
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3190726/ https://ncbi.nlm.nih.gov/pubmed/21586567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.208249 |
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