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Matrix Gla Protein Metabolism in Vascular Smooth Muscle and Role in Uremic Vascular Calcification

Matrix Gla protein (MGP) is an inhibitor of vascular calcification but its mechanism of action and pathogenic role are unclear. This was examined in cultured rat aortas and in a model of vascular calcification in rats with renal failure. Both carboxylated (GlaMGP) and uncarboxylated (GluMGP) forms w...

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Main Authors: Lomashvili, Koba A., Wang, Xiaonan, Wallin, Reidar, O'Neill, W. Charles
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190679/
https://ncbi.nlm.nih.gov/pubmed/21705322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.251462
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