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Effect of bisphosphonates on vascular calcification and bone metabolism in experimental renal failure

Although it is known that bisphosphonates prevent medial vascular calcification in vivo, their mechanism of action remains unknown and, in particular, whether they act directly on the blood vessels or indirectly through inhibition of bone resorption. To determine this, we studied the effects of two...

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Main Authors: Lomashvili, Koba A., Monier-Faugere, Marie-Claude, Wang, Xiaonan, Malluche, Hartmut H., O’Neill, W. Charles
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2999577/
https://ncbi.nlm.nih.gov/pubmed/19129793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2008.646
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