Identification of sodium channel isoforms that mediate action potential firing in lamina I/II spinal cord neurons

BACKGROUND: Voltage-gated sodium channels play key roles in acute and chronic pain processing. The molecular, biophysical, and pharmacological properties of sodium channel currents have been extensively studied for peripheral nociceptors while the properties of sodium channel currents in dorsal horn...

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Autori principali: Hildebrand, Michael E, Mezeyova, Janette, Smith, Paula L, Salter, Michael W, Tringham, Elizabeth, Snutch, Terrance P
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190347/
https://ncbi.nlm.nih.gov/pubmed/21910862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-7-67
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