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Identification of sodium channel isoforms that mediate action potential firing in lamina I/II spinal cord neurons

BACKGROUND: Voltage-gated sodium channels play key roles in acute and chronic pain processing. The molecular, biophysical, and pharmacological properties of sodium channel currents have been extensively studied for peripheral nociceptors while the properties of sodium channel currents in dorsal horn...

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Autors principals: Hildebrand, Michael E, Mezeyova, Janette, Smith, Paula L, Salter, Michael W, Tringham, Elizabeth, Snutch, Terrance P
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190347/
https://ncbi.nlm.nih.gov/pubmed/21910862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-7-67
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