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Identification of FUSE-binding protein 1 as a regulatory mRNA-binding protein that represses nucleophosmin translation

Nucleophosmin (NPM/B23) is a multifunctional oncoprotein whose protein expression levels dictate cellular growth and proliferation rates. NPM is translationally responsive to hyperactive mammalian target of rapamycin (mTOR) signals, but the mechanism of this regulation is not understood. Using chime...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Olanich, Mary E., Moss, Britney L., Piwnica-Worms, David, Townsend, R. Reid, Weber, Jason D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190308/
https://ncbi.nlm.nih.gov/pubmed/20802533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.404
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