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Identification of FUSE-binding protein 1 as a regulatory mRNA-binding protein that represses nucleophosmin translation
Nucleophosmin (NPM/B23) is a multifunctional oncoprotein whose protein expression levels dictate cellular growth and proliferation rates. NPM is translationally responsive to hyperactive mammalian target of rapamycin (mTOR) signals, but the mechanism of this regulation is not understood. Using chime...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3190308/ https://ncbi.nlm.nih.gov/pubmed/20802533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.404 |
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