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β-Amyloid peptide blocks the response of α7-containing nicotinic receptors on hippocampal neurons

Alzheimer's disease produces a devastating decline in mental function, with profound effects on learning and memory. Early consequences of the disease include the specific loss of cholinergic neurons in brain, diminished cholinergic signaling, and the accumulation of β-amyloid peptide in neurit...

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Autors principals: Liu, Qing-song, Kawai, Hideki, Berg, Darwin K.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2001
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC31903/
https://ncbi.nlm.nih.gov/pubmed/11274373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.081553598
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