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Comprehensive analysis of microRNA genomic loci identifies pervasive repetitive-element origins

MicroRNAs (miRs) are small non-coding RNAs that generally function as negative regulators of target messenger RNAs (mRNAs) at the posttranscriptional level. MiRs bind to the 3′UTR of target mRNAs through complementary base pairing, resulting in target mRNA cleavage or translation repression. To date...

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Autors principals: Borchert, Glen M, Holton, Nathaniel W, Williams, Jonathan D, Hernan, William L, Bishop, Ian P, Dembosky, Joel A, Elste, James E, Gregoire, Nathaniel S, Kim, Jee-Ah, Koehler, Wesley W, Lengerich, Joe C, Medema, Arianna A, Nguyen, Marilyn A, Ower, Geoffrey D, Rarick, Michelle A, Strong, Brooke N, Tardi, Nicholas J, Tasker, Nathan M, Wozniak, Darren J, Gatto, Craig, Larson, Erik D
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190270/
https://ncbi.nlm.nih.gov/pubmed/22016841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mge.1.1.15766
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