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In Vivo Olfactory Model of APP-Induced Neurodegeneration Reveals a Reversible Cell-Autonomous Function

Amyloid precursor protein (APP) has long been linked to the neurodegeneration of Alzheimer's disease (AD), but the associated cell death has been difficult to capture in vivo, and the role of APP in effecting neuron loss is still unclear. Olfactory dysfunction is an early symptom of AD with amy...

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Détails bibliographiques
Auteurs principaux: Cheng, Ning, Cai, Huaibin, Belluscio, Leonardo
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190161/
https://ncbi.nlm.nih.gov/pubmed/21957232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1714-11.2011
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