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Crystal structure of New Delhi metallo-β-lactamase reveals molecular basis for antibiotic resistance

β-Lactams are the most commonly prescribed class of antibiotics and have had an enormous impact on human health. Thus, it is disquieting that an enzyme called New Delhi metallo-β-lactamase-1 (NDM-1) can confer Enterobacteriaceae with nearly complete resistance to all β-lactam antibiotics including t...

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Bibliografiske detaljer
Main Authors: King, Dustin, Strynadka, Natalie
Format: Artigo
Sprog:Inglês
Udgivet: Wiley Subscription Services, Inc., A Wiley Company 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190144/
https://ncbi.nlm.nih.gov/pubmed/21774017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.697
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