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Acylpeptide Hydrolase Inhibition as Targeted Strategy to Induce Proteasomal Down-Regulation
Acylpeptide hydrolase (APEH), one of the four members of the prolyl oligopeptidase class, catalyses the removal of N-acylated amino acids from acetylated peptides and it has been postulated to play a key role in protein degradation machinery. Disruption of protein turnover has been established as an...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3189933/ https://ncbi.nlm.nih.gov/pubmed/22016782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025888 |
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